Characterization of an aryl piperazine/2-hydroxypropyl-β-cyclodextrin association, a complex with antidiabetic potential
نویسندگان
چکیده
منابع مشابه
Solid State Characterization of Domperidone: Hydroxypropyl-β-Cyclodextrin Inclusion Complex
The purpose of the present study was to prepare inclusion complex of domperidone with hydroxylpropyl-β-cyclodextrin in order improved the solubility and hence to increase dissolution of domperidone. An effect of concentration of hydroxylpropyl-β-cyclodextrin on the aqueous solubility of domperidone was determined by phase-solubility method. The aqueous solubility of domperidone increased as a f...
متن کاملDevelopment and Characterization of Paracetamol Complexes with Hydroxypropyl-?-Cyclodextrin
Paracetamol is a sparingly soluble bitter tasting drug. It is widely used as an analgesic and antipyretic. Complexation of drug with different cyclodextrins (?, ? and HP-?-CD) was attempted to improve solubility of Paracetamol. During the drug excipient interaction studies, ?, ? cyclodextrins elicited analytical interference and showed considerable absorbance at ?max (243.5 nm) of Paracetamol w...
متن کاملDevelopment and Characterization of Paracetamol Complexes with Hydroxypropyl-?-Cyclodextrin
Paracetamol is a sparingly soluble bitter tasting drug. It is widely used as an analgesic and antipyretic. Complexation of drug with different cyclodextrins (?, ? and HP-?-CD) was attempted to improve solubility of Paracetamol. During the drug excipient interaction studies, ?, ? cyclodextrins elicited analytical interference and showed considerable absorbance at ?max (243.5 nm) of Paracetamol w...
متن کاملCharacterization and Antioxidant Activity of the Complex of Phloridzin and Hydroxypropyl-β- cyclodextrin
Purpose: To improve the aqueous solubility of phloridzin by complexing it with hydroxypropyl-βcyclodextrin (HP-β-CD). Methods: The complex of phloridzin with HP-β-CD was prepared by freeze-drying method. The physicochemical properties of the complex were investigated by ultraviolet-visible spectrometry (UV), infrared spectrometry (IR), differential scanning calorimetry (DSC) and x-ray diffracto...
متن کاملCytotoxicity and Phototoxicity of Chlorophyll a/Hydroxypropyl-γ-cyclodextrin Complex on Leishmania Major Promastigotes
Introduction: Cutaneous leishmaniasis (CL) is a widespread disease that is epidemic in Iran, too. Photodynamic therapy (PDT) is an attractive modality to treat cancer and hyper proliferative diseases based on the use of a photosensitizer in the presence of oxygen and proper wavelength of light. In consideration of lesion location, lack of systemic involvement and inefficiency of current treatme...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Results in Chemistry
سال: 2020
ISSN: 2211-7156
DOI: 10.1016/j.rechem.2020.100026